Download of SPINA_Thyr_V4_0_Handbook.pdf (SPINA_Thyr_V4_0_Handbook.pdf ( external link: SF.net): 585,428 bytes) will begin shortly. If not so, click link on the left.
SPINA is software for determining constant structure-parameters of endocrine feedback control systems from hormone levels obtained in vivo. The first version of this cybernetic approach allows for evualuating the functional status of the thyroid gland, i.e. thyroid's secretory capacity (GT or SPINA-GT) and sum activity of peripheral deiodinases (GD or SPINA-GD).
